Dovobet is the trade name for a topical treatment that combines a potent steroid with calcipotriol (Dovonex). It is generally used for plaque psoriasis and is initially prescribed for 4 weeks. It appears to work more quickly than Dovonex, but, owing to the fact that it contains potent steroid, it should not be used for prolonged periods of time. The maximum dose is 100 g per week.
Dithrocream is a type of dithranol that is very helpful in treating well-defined and easily accessible areas of psoriasis, such as those on the elbows and knees. The ‘short-contact’ approach has been designed for use at home as it is less messy than the paste forms of dithranol used in hospital. It involves applying gradually increasing strengths of Dithrocream to the plaques of psoriasis and leaving the cream in place before washing it off
Apply enough to cover the plaque completely, and rub the cream in until it is completely absorbed. The first strength is usually 0.1%, followed by 0.25%, and going up to 2%. One reason for gradually increasing the strength is to minimise the likelihood of your skin becoming sore. The Dithrocream must be applied carefully to the plaques, not the good skin, making sure that it does not smudge. It should then be washed off after half an hour and moisturisers reapplied. This only needs to be done once a day. Always remember to wash your hands thoroughly after applying treatment. You may wish to wear plastic gloves to avoid staining your fingertips.
In general, your doctor will prescribe you different creams for your knees/elbows and for your genital area. The skin in the genital area is thinner and therefore more sensitive than that on your elbows/ knees so is more likely to be irritated. Using the same treatment there may actually cause damage and soreness. There is also the fact that the genital area tends to be warm and moist, which means that the treatment is absorbed more readily and therefore does not need to be as strong to be effective. Mild-to-moderate-potency steroids are often used in the genital and other flexural areas (e.g. the armpits) and, because infections with yeasts and bacteria are common in these places, are often combined with antifungal and antibacterial agents.
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